Iowa State has lost its last eight games at West Virginia and is 2-9 there all-time. The Cyclones have outscored Big 12 foes by an average of 14 points per game. WVU is coached by Darian DeVries, who left Drake in March. He was 150-55 over six seasons at Drake, and led the Bulldogs to three NCAA tournament appearances.

Top-ranked teams in the Big 12 meet. We continue our College Basketball odds series with a Iowa State-West Virginia prediction and pick.

Catch all the action between the Kansas Jayhawks and the Iowa State Cyclones in this ranked college basketball matchup live on Wednesday.

Iowa State secured its 12th straight win when they dominated the Jayhawks over the final 20 minutes, remaining unbeaten in Big 12 Conference play. The only loss to date came at th