San Antonio, or unofficially "San Ann" or "San An" as the locals call it, is a city in Pasco County, Florida, United States. It is a suburban city incl…San Antonio, or unofficially "San Ann" or "San An" as the locals call it, is a city in Pasco County, Florida, United States. It is a suburban city included in the Tampa-St. Petersburg-Clearwater, Florida Metropolitan Statistical Area, much more commonly known as the Tampa Bay Area. It lies within Florida's 12th congressional district. The population was 1,297 at the 2020 census.